A 48-year-old male with HIV/AIDS presented with an enlarging nodular lesion on the base of his penis.Histology revealed changes heat experience sitteunderlag consistent with chronic viral infection and culture grew herpes simplex virus 2 (HSV-2).The lesion was refractory to valacyclovir and intralesional (IL) cidofovir therapy.Urology excised the mass and the defect was repaired primarily with good cosmetic result.
Post-operative pathology confirmed HSV-2 despite the unusual appearance of the lesion consisting of nodular mass without rike knife lamella gross ulceration.